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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e112241eab585b05ffeda389cfb23bc0dbd1d0ae26a85572f91ead1ebfc32db7' 
  AND token = 'fNLL6QgOwTEo9M3x0HpgXrK0wjO/8s+SZP5OZ/uzQNY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}