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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec06edd5692c316b74a8bdb47a8a5378c037cc5c1f31ffb5e588dc6d3729aeed' 
  AND token = 'aHfgRSpx66Inqbc6ZwrzBw+DqFrwt1Uees2lCy5UdWs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}