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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '331e35f2d176bee9f8c661c3518ce28a87bb58bfdeb33d9d9a213b0a81a87002' 
  AND token = 'vo55DRRMp+R2kk4/HBZGE4Uc909qS2Y9zPjLHSyx7hs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}