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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fcc4a3b20a2e45d23c054900a65ae9f2480b03da8361d9407b4209f77a810d61' 
  AND token = '5QfoImfEKTN4o4lxcxf2sH5yJU+p9c9jCHJ/9Q79dEM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}