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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20f1e86236900e45ec831efc979317372db7836fac7420c9a1aebea6b37e6dec' 
  AND token = 'zde+6GxD9Pshaay6axjPiXLb37UHeeX9OG3LYOdrPzM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}