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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05151b5e6ae6bbc9fcf4a52de8c72ee2276d504d622f4bf2c41d27f9b55ef279' 
  AND token = '2IhHNi8xvBLGqE4EavIiajoxrK8xpyXrlOkV9wad1+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}