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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78392effd3474936303744953a85021b5442956beee64a58ea7e2301a6fe3910' 
  AND token = '1n+VvxGabgQ0/K+DvahQSjac4pNPysKtVV0dSprcRCc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}