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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f694f0df3e11685fd2641e2d4b71260e8f09f64642430df2694d5517cbe94e03' 
  AND token = 'MqRvheagbJztc+SOqQewaqAqN1vbcesPK3YBqd5Mvbk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}