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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '580d48e2033e6057ce6a84ac4924310bacd2651ea69a6b7a5b8e94f096b27115' 
  AND token = '1LBeRXZKj4O8dCDnyVm1IOjce/s4rXyOfRy7HJ7ocLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}