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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db8e08b1a8620fc16c50964e7dcd8291426b9552678951534df6d61a3c8209b9' 
  AND token = '2RhRfFRAtcnctZUfD6WjWj8KTES5Y1SN9z1EMLvuHyk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}