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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '580fb071a40c99c4eeb4bf9351f0ee586c39204877d0173901b84a7e631996fc' 
  AND token = 't4FtVAkoMvWCXHf+kZ3Lvh3eBxf4tJ7bd+h5CyogPOo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}