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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a2e72dcec4b8421874eee83b65a0e358e7de3acd120c653d7359febd7a61fdf' 
  AND token = 'Qq+qzMwIy69WJDE5HrEHj0aKDUGyguF381OKMtwGYh4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}