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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b73965acce77946b085adc7e6508feb8d17c6a9ca6acf289ab3ca2fc33f912d' 
  AND token = 'Rr1+k3TEh6sKCaqP36tHJLqmQddDumWsRrfP7ASyVsI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}