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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '165ad3f59639b4c633d6ce9098a716adf21ed36d10c22325501bba543c3adb3c' 
  AND token = 'DRNLDSLNvaj0BiLufCOZygSyAwbvJv58WIkIr2dvCzY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}