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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79a53d8f14dfa51b02d8f64baab08d7e8d012e158e2a1b5fd87a19ccf426719a' 
  AND token = 'vuoIxPG0HVq9bLRMhx169SSzzjFFMEQvdKiR5UxBOnc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}