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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8493b7059d01972068469497000a1a4c4c94a4357ca57f5fde6cb3c87a63b866' 
  AND token = 'D+AGdR6hrk4NEPLQeyZpwCO2fI/kx6RCOeUVux7CT5c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}