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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2411242ad0cb8e9ecab89619d4aa350922fdfdcd273f1d50a4d2233a225b85d' 
  AND token = '4xaTH0f3KfsT/Iih14SVVxQmeDRUNlqlNuV0u7sLmd4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}