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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df5f22a6407e9535d20b4007d3bb6eebf78e02f3e5f5252e51c1749bb14dc596' 
  AND token = 'H6lxbIWeTyXK2BUrsG9KolQORNsAutH0bwpK5DB8Xh8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}