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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88a48164cf1090675a00aad9199aa56921403633ebae0f56b1d563d6a73e3431' 
  AND token = 'Vizh2Ps0fwE3wcBvj6JxV4ND+P6DbM7U6B95AnppNKs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}