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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce76ce71360afdeb09392c483ad25a9d0ef4bd2ab1696ec0c65260d7250508ea' 
  AND token = 'ubHj1bDr5gu/WPX8E51ZLWaHjSZHcjNgpxAC90MiMjw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}