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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc6df728cb3dea8cad718880e2286e3fbade6ea282334ec550cafb036e7fecf6' 
  AND token = 'XgWI7Ok45b59hy1eAFFi3yickbfUQkb55ZaF+tIzzKQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}