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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc737ef72b32bfe75a2b5320c6344e9a3d65ce666385d62de1ab35c1224d9bca' 
  AND token = 'v9I+JsdXGRQTarqf1JBOO5sGtevROsV0s7JB3ZsAe4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}