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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7cd43311fe9b78ee9743117517820c03ea8f0adb24fe5bcb56c1aa056798643' 
  AND token = '00J7+3UCeongDGVnSybE/aOBz1B19J87Vcp05CZDwVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}