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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e06cc972f14924713d9a59aa86604b1f43d414ece8e51da5098e961a63277d6' 
  AND token = 'bHOvTV1oi3VDcOwvemfSpyeiDfzvN2b1mY2Bzt+i6fk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}