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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81cd7fd182ed984a29ee55a9bd51c3dcd00b898d8b214e34326ab0c1f2124004' 
  AND token = 'qQJ8sMWKPW0ID0q2wkr8fO69Rwuq/NOrqvVCk/TFRNU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}