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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3b6d09409c73f4700c7019108fd81042f90ddb49b8e8128009d03237ed04727' 
  AND token = '5EGIyTm1io+Awgy82GAuX1m6gwlgkyNxvR1tmpsZWTc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}