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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '227c9106c5dc0b278843937e1c487004071b1c1b7ec76998d16f9be751e93fd4' 
  AND token = '2+VIlaYKb0XGtl/bL3hg8Vc5aY8ggT0psYdG0PBfQkU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}