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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27614c41f84dcf774a32c017cc0e0474f366ad5cf61726bab847ad755ea370f9' 
  AND token = '1z4R+ogLXpY04pdm8L4l58OMoqBqCTQr2bi8jeWho3I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}