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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e9a10168d0b358208242019ff9c6a05b92dcbac0e09144a31ca1077268c49f4' 
  AND token = 'Ur5UpsKilctp6lXv4F8yRVkk61hp5VRn9RC8WyeCd0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}