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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5dd637b72e022e8c9fb4ea4fcf243811f437d404ddbff407fadf959c24789d1d' 
  AND token = '+a1B10BZ3tEsc1w+W/4fcOcg95dW3l89sTYKpdZkq3M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}