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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c01a48d754cfde083d3d09388fa4d9c407aba4a22ccd80af71adc39038ce3639' 
  AND token = 'PYNbiR5/YAeHntFJQS00+EX+I1HGiBnG9Wq4BD++1Io=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}