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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e5dedb064c1bba520c7919d4297bd86a6ecf7c96b2b445c3f82bece4651beb9' 
  AND token = 'e5LbRtEQ23+g8wjzjqLbrOEfyYugDgbL8xti+0Je3zY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}