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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2aee746c57e14b9471690c0f31548f7e52b6b695023edbc3c3f2d226b3b9506d' 
  AND token = 'GNcTio4T551SLG3pHJMX1wN2QQZCggh8May26a+xdpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}