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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48ba9aff263f759537a2c8280f08738c7644f4c3ceadd9fcaad18fe53152e2ee' 
  AND token = 'm0O5QN9/yxgfC+c67HuvRvdps1mvEi8XgAClfu/vyEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00061

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}