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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2101e902e6498e1027e4875cdca57da0aa4575007eb2b8fa22d84590f4f8caef' 
  AND token = 'i3KqlkIhfZFNomzLoiXdpgdNt1PZDM/cnlAYds62CjM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}