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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7ed5fa4728a90a608059112d100f9fd7cd97ead3f452d9e2c1d54632f47285e' 
  AND token = 'gMz0GDkryfBxBDIWoa68yP1+w/odSgAVL5yS3Z5ByqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}