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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2661de8f9ebff51e1813e6b6458c8e53be8af98c6f4979c8e056881d3d9ec531' 
  AND token = 'vkdbgarLmieC6u0haJpCzlzVooJPABhe52nLgj3Th74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}