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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad2b19a901a38d3701308c9a5c2d50c51063185d07f924fe331e53133daa48b8' 
  AND token = 'RDAkZsHTdKWqrybQt7rR1MRTpxqhgTu4tCbXIhGoB2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}