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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de4db76c9490a209e9866580dd43b44bd6887919edfbc1bd68c056fcfca09ad7' 
  AND token = 'R0ItjyNA7Yz7BwyueNkxFO5TdaeqzyLAiRqbcJNlHik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}