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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4d0878c2c04e2f1fe117cc64090d91c906fea9e33aab3e0cce5ec2bb0a8f01e' 
  AND token = '7e48tOSW2xNbPZzuXOsIsaLgQKFMWSSgwFl33EGA+rQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}