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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e45c5921b080d6f98e927b57af067d6d9cd83ab1732a0b6dbc6ae55a234b0ec' 
  AND token = 'M3VpLmHdAjank9J1IA6zqLA+OPEE/2zmSJzm12JqUkg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}