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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8649345e0ee8b2442b19f454c66eab6bda5a32e26389cff5a27e0ccb3ff99360' 
  AND token = 'X33R/DZcALNgKLyDqw2XDiyo3y06UGIFsZYblTHFdCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}