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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b86e9b74da95da5c8c4e291b618df1ae21979e49ca7a0dd5378360b499e55388' 
  AND token = 'gxVm4u3D1ixx4dNC5rhcDA3YFzV3yF11cJ99vU/NvXE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}