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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e2954561df08e81de1ebd3bc33d28a7b5a1328401962dc480a498d6d888c648' 
  AND token = 'NIrvqNQORh5WT/6Qbdrghm+w1BbFxee7eKxd8FZdHwM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}