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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '817ef60aa6c3f501cb21331f5820108309f9620503615076bd821830d62ef311' 
  AND token = 'Q31UOXOX9Y+oUHuYR9AZF2V/ZP7+b/zOSDYVceuxcec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}