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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bb2e2238a8bb61fd60722a26a0acddf256e136fc56dbfe9aebf272c3c2062bc' 
  AND token = 'IwiP+K419cF7DCqoHE0yVabrheSoSXPCJb/CYXVdRdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}