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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7335f993d0db7df75db298639eda07c3187b1eed2321543924206cfee9089ab3' 
  AND token = '4yMS6qJ2Pekg4e4kZswNWmulGrXK7rsroel1gbN6YIE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}