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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '32d34d69bd6ca401ce7aa2a242e7cb4366457d35cf5f486dfa10ab106163fece' 
  AND token = '+Gu91kUlDeF3F7w/Tzc/nW4DGwVIpQb2y63s7G+yTNM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}