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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0066708a7c521cc95d31cf57132f5d156a7138d9f65dd646c386e9e29e85fdbe' 
  AND token = 's4efVdKoCJM4n1Mzfox18eZWPfE6/U6DAGn8ye6zO70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}