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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10e7ab63c09d0163d95a962da0fd0077b23e582c29b9f55b7bf43d2d43c36ee7' 
  AND token = 'nYVB6v+hL1r8aTN4EbRIbN0TUuMYhyc9cHR2ysQbOXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}